Table of Contents

2017 Month : April Volume : 3 Issue : 1 Page : 7-10.

ROLE OF RAPID IMMUNOCHROMATOGRAPHIC TEST IN SERODIAGNOSIS OF CHIKUNGUNYA INFECTION IN A TERTIARY CARE CENTRE.

Shavi Nagpal1, Aroma Oberoi2

Corresponding Author:
Dr. Aroma Oberoi,
Department of Microbiology,
Christian Medical College and Hospital,
Ludhiana, Punjab.
E-mail: draromaoberoi@yahoo.com

ABSTRACT

BACKGROUND

A large number of arthropod borne viruses (Arboviruses) have been diagnosed from humans in India in recent years. In India, there was a major outbreak of Chikungunya in 2006 wherein 1.39 million cases were diagnosed across 16 states. The main clinical features in this self-limiting disease include sudden onset fever, chills, rash and joints pain. A study was done to look for the seropositivity of Chikungunya IgM card test (Immunochromatographic assay) among suspected test samples.

MATERIALS AND METHODS

This is a hospital based study done in the Department of Microbiology at a tertiary care centre in Ludhiana from September to December 2016. A total of 481 blood samples from patients with suspected chikungunya were sent to the Microbiology Laboratory for detection of IgM Ab.

RESULTS

A total of 481 clinical samples were tested for Chikungunya IgM Ab during the study period. Majority of the samples (449) were from adults (93.3%), while only 32 samples (6.65%) were of paediatric age groups. Out of all samples, majority (420 out of 481, i.e. 87.3%) were from inpatient wards. A total of 87 patients were tested “Reactive” out of 481 (18.08%) and among them Male-to-Female ratio was 1.6:1.

CONCLUSION

Immunochromatographic test for IgM Ab against chikungunya virus has advantage of being rapid, easy, user friendly and does not require special equipment or training. It can be used as rapid tool for confirmation of diagnosis. However, its sensitivity and specificity needs to be determined and physicians should refrain from advising the test during first 3 - 4 days of illness.

Keywords

Chikungunya, Arbovirus, Chikungunya IgM Ab, Immunochromatographic Assay.

Videos :

watch?v

Download Download [ PDF ] Download[ ABSTRACT ] Email Send to a friend